Ketof-DT Tablet contains Ketorolac 10mg, a potent nonsteroidal anti-inflammatory drug (NSAID) indicated for the short-term management of moderate to severe pain. Ketorolac exerts its therapeutic effect by inhibiting cyclooxygenase (COX-1 and COX-2) enzymes, leading to decreased synthesis of prostaglandins, which are mediators of inflammation, pain, and fever. This medication is commonly prescribed for postoperative pain relief and other acute painful conditions where opioid alternatives are preferred. Ketof-DT should be used at the lowest effective dose for the shortest duration, typically not exceeding five days, to minimize the risk of adverse effects. Contraindications include hypersensitivity to ketorolac or other NSAIDs, active peptic ulcer disease, recent gastrointestinal bleeding, severe renal impairment, and patients at risk of bleeding. Common side effects may include gastrointestinal discomfort, nausea, headache, dizziness, and, less frequently, renal dysfunction or hypersensitivity reactions. Caution is advised in patients with cardiovascular disease, hypertension, or those receiving concomitant anticoagulant therapy. Ketof-DT is contraindicated during labor, delivery, and in patients with established cerebrovascular bleeding. Proper patient evaluation and monitoring are essential to ensure safe and effective use of Ketorolac 10mg tablets.