Ketamide-AD Shampoo is a medicated topical formulation containing Ketoconazole 2% w/v and Zinc Pyrithione 1% w/v, designed for the treatment of dandruff and seborrheic dermatitis. Ketoconazole, an imidazole antifungal agent, exerts its effect by inhibiting the synthesis of ergosterol, an essential component of fungal cell membranes, thereby disrupting fungal growth and proliferation. Zinc Pyrithione possesses antibacterial and antifungal properties, effectively reducing scalp flaking, itching, and inflammation associated with seborrheic conditions. The combined action of these active ingredients provides a broad-spectrum approach to managing scalp disorders caused by Malassezia species and other microbial agents. Ketamide-AD Shampoo is indicated for patients experiencing moderate to severe dandruff, seborrheic dermatitis, and related scalp conditions characterized by erythema, scaling, and pruritus. The shampoo is intended for topical use only and should be applied to wet hair, massaged into the scalp, left for 3 to 5 minutes, and rinsed thoroughly. Regular use as directed by a healthcare professional can lead to significant improvement in symptoms and prevention of recurrence. Caution is advised in patients with hypersensitivity to any component, and use should be discontinued if irritation occurs. This product is not intended for use on broken or inflamed skin.