Ketafung Lotion contains Ketoconazole 2% w/v, an imidazole antifungal agent effective against a broad spectrum of dermatophytes, yeasts, and molds. It is primarily indicated for the treatment of superficial fungal infections of the skin, including tinea corporis, tinea cruris, tinea pedis, and pityriasis versicolor. Ketoconazole exerts its antifungal activity by inhibiting the synthesis of ergosterol, an essential component of fungal cell membranes, leading to increased membrane permeability and cell death. The lotion formulation allows for easy topical application, promoting rapid absorption and targeted action at the site of infection. Ketafung Lotion is generally well tolerated, with minimal systemic absorption reducing the risk of systemic side effects. Common adverse reactions may include mild local irritation, burning sensation, or itching at the application site. It is recommended to apply the lotion once or twice daily to the affected area for a duration of 2 to 4 weeks, depending on the severity and type of infection. Patients should avoid contact with eyes and mucous membranes. Ketafung Lotion should be used under medical supervision, especially in cases of extensive or resistant infections. Proper hygiene and adherence to treatment are essential to prevent recurrence.