K-Less Sachet contains Calcium Polystyrene Sulphonate 15gm, an ion-exchange resin used primarily for the treatment of hyperkalemia, a condition characterized by elevated potassium levels in the blood. This medication functions by exchanging calcium ions for potassium ions in the gastrointestinal tract, thereby facilitating the removal of excess potassium through fecal excretion. K-Less Sachet is indicated in patients with chronic kidney disease, acute kidney injury, or other conditions that predispose to hyperkalemia, including certain medication regimens that impair potassium excretion. The sachet formulation allows for convenient oral administration, with the powder dissolved in water prior to ingestion. Dosage and duration of treatment should be individualized based on the severity of hyperkalemia and patient response, under strict medical supervision. Adverse effects may include gastrointestinal disturbances such as constipation, nausea, or abdominal discomfort; rare cases of intestinal necrosis have been reported, necessitating careful monitoring. K-Less Sachet is contraindicated in patients with hypocalcemia, bowel obstruction, or known hypersensitivity to calcium polystyrene sulphonate. It is essential to monitor serum electrolytes regularly during therapy to avoid electrolyte imbalances. This medication should be used cautiously in patients with impaired gastrointestinal motility or severe constipation.