Justempa-LN 25/5 Tablet
Justempa-LN 25/5 Tablet
Empagliflozin (25mg) + Linagliptin (5mg)
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About This Medicine
Product description & overview
Justempa-LN 25/5 Tablet is a combination oral antidiabetic medication containing Empagliflozin 25 mg and Linagliptin 5 mg, indicated for the management of type 2 diabetes mellitus. Empagliflozin, a sodium-glucose co-transporter 2 (SGLT2) inhibitor, reduces renal glucose reabsorption, promoting urinary glucose excretion and thereby lowering blood glucose levels. Linagliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor, enhances incretin hormone activity, which increases insulin secretion and decreases glucagon release in a glucose-dependent manner. The synergistic action of these agents improves glycemic control without significant risk of hypoglycemia when used appropriately. Justempa-LN 25/5 is typically prescribed as an adjunct to diet and exercise in adults inadequately controlled on monotherapy or other antidiabetic agents. It is contraindicated in patients with type 1 diabetes, diabetic ketoacidosis, or severe renal impairment. Common adverse effects may include urinary tract infections, nasopharyngitis, and gastrointestinal disturbances. Regular monitoring of renal function, blood glucose, and signs of volume depletion is recommended during therapy. This combination offers a convenient once-daily dosing regimen, improving patient adherence and overall management of type 2 diabetes mellitus.
Active composition
Empagliflozin 25 mg
+1 more active ingredient
About Empagliflozin
Empagliflozin is used to treat Type 2 diabetes. It works by inhibiting glucose reabsorption in the kidneys, promoting glucose excretion. Empagliflozin is effective in managing blood sugar levels. In summary, it plays a vital role in diabetes management.
How It Works
Empagliflozin inhibits the sodium-glucose co-transporter 2 (SGLT2) in the renal proximal tubules, reducing glucose reabsorption and increasing urinary glucose excretion.
All Active Ingredients
Linagliptin
Linagliptin inhibits the enzyme DPP-4, leading to increased levels of incretin hormones, which promote insulin secretion and inhibit glucagon release, thereby lowering blood glucose levels.
Dosage & How to Use
Dosage information not available. Please consult your doctor or pharmacist.
Safety Advice
Important precautions
Side Effect Occurrence
Based on clinical trials and patient reports.
Overall Tolerance
Most patients tolerate well
Common Side Effects
Safety Advice
Alcohol
It is unsafe to consume alcohol with Justempa-LN 25/5 Tablet.
High Risk
Pregnancy
Justempa-LN 25/5 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
Driving
It is not known whether Justempa-LN 25/5 Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Exercise Caution
Liver
Justempa-LN 25/5 Tablet is safe to use in patients with liver disease. No dose adjustment of Justempa-LN 25/5 Tablet is recommended. However, the use is not recommended in severe hepatic impairment due to the lack of studies performed in such cases.
Regular Checkup
Breastfeeding
Justempa-LN 25/5 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Consult Doctor
Kidney
Justempa-LN 25/5 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Justempa-LN 25/5 Tablet may be needed. Please consult your doctor. Use of Justempa-LN 25/5 Tablet is contraindicated in patients with severe kidney disease or in dialysis.
Regular Checkup
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