Jointace-DN Super Tablet is a combination pharmaceutical formulation containing Diacerein 50 mg and Glucosamine 1500 mg, designed to support joint health and manage symptoms associated with osteoarthritis. Diacerein, an anthraquinone derivative, exhibits anti-inflammatory and chondroprotective properties by inhibiting interleukin-1 beta, thereby reducing cartilage degradation and alleviating pain and inflammation in affected joints. Glucosamine, a naturally occurring amino monosaccharide, serves as a key substrate for the biosynthesis of glycosaminoglycans and proteoglycans, essential components of cartilage matrix, promoting cartilage repair and maintenance. The synergistic action of Diacerein and Glucosamine in Jointace-DN Super Tablet aids in improving joint function, reducing stiffness, and enhancing mobility in patients with degenerative joint diseases. This formulation is indicated for the symptomatic treatment of osteoarthritis of the knee and other joints, providing both symptomatic relief and potential disease-modifying effects. Jointace-DN Super Tablet should be used under medical supervision, with consideration of patient-specific factors such as comorbidities and concomitant medications. Common adverse effects may include gastrointestinal disturbances; therefore, adherence to prescribed dosage and monitoring is recommended to optimize therapeutic outcomes and minimize risks.