Jeyderm-Plus Cream is a topical formulation combining Clobetasol propionate (0.05% w/w), Neomycin sulfate (0.5% w/w), Miconazole nitrate (2% w/w), and Chlorocresol (0.1% w/w), designed for the management of inflammatory and infectious dermatological conditions. Clobetasol, a potent corticosteroid, exerts strong anti-inflammatory, antipruritic, and vasoconstrictive effects, providing rapid relief from redness, swelling, and itching associated with various dermatoses. Neomycin, an aminoglycoside antibiotic, targets a broad spectrum of gram-negative and some gram-positive bacteria, preventing or treating secondary bacterial infections. Miconazole, an imidazole antifungal agent, is effective against dermatophytes, yeasts, and molds, addressing fungal components of mixed infections. Chlorocresol serves as a preservative, ensuring product stability and preventing microbial contamination. Jeyderm-Plus Cream is indicated for use in inflammatory dermatoses complicated by bacterial and fungal infections, such as eczema, psoriasis, and dermatitis with secondary infections. It should be applied topically as directed by a healthcare professional, avoiding prolonged use to minimize potential corticosteroid-related adverse effects. Caution is advised in patients with hypersensitivity to any components, and it is not recommended for use on extensive body areas or mucous membranes. Proper medical supervision is essential to optimize therapeutic outcomes and reduce risks.