Jankey 100mg Tablet contains Sitagliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor used in the management of type 2 diabetes mellitus. Sitagliptin works by enhancing the levels of incretin hormones, which increase insulin release from pancreatic beta cells and decrease glucagon secretion from alpha cells in a glucose-dependent manner. This dual action helps to improve glycemic control without causing significant hypoglycemia. Jankey 100mg is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes, either as monotherapy or in combination with other antidiabetic agents such as metformin, sulfonylureas, or insulin. The recommended dose is typically 100 mg once daily, with dose adjustments required in patients with moderate to severe renal impairment. Common adverse effects may include nasopharyngitis, headache, and upper respiratory tract infections, while serious side effects are rare but can include pancreatitis and hypersensitivity reactions. Jankey 100mg should be used cautiously in patients with a history of pancreatitis and monitored regularly for efficacy and safety. It is not indicated for type 1 diabetes or diabetic ketoacidosis. Patient adherence to prescribed lifestyle modifications alongside medication is essential for optimal therapeutic outcomes.