Itrol 100 Capsule contains Itraconazole 100 mg, a broad-spectrum triazole antifungal agent effective against a variety of fungal infections. Itraconazole works by inhibiting the synthesis of ergosterol, an essential component of fungal cell membranes, thereby disrupting membrane integrity and leading to fungal cell death. Itrol 100 is indicated for the treatment of systemic and superficial mycoses including aspergillosis, blastomycosis, histoplasmosis, onychomycosis, and other dermatophytic infections. The capsule formulation ensures optimal bioavailability and convenient oral administration. Itrol 100 should be taken with food to enhance absorption. Dosage and duration depend on the type and severity of infection and should be determined by a healthcare professional. Common adverse effects may include gastrointestinal disturbances such as nausea, vomiting, abdominal pain, and diarrhea, as well as headache and rash. Rare but serious side effects include hepatotoxicity and congestive heart failure; therefore, liver function tests and cardiac status should be monitored during prolonged therapy. Itrol 100 is contraindicated in patients with hypersensitivity to itraconazole or other azole antifungals and should be used cautiously in patients with liver impairment. Drug interactions are significant due to itraconazole’s inhibition of cytochrome P450 enzymes; thus, concomitant use with certain medications requires careful evaluation.