Itrez 100 Capsule contains Itraconazole 100 mg, a broad-spectrum triazole antifungal agent used for the treatment of various systemic and superficial fungal infections. Itraconazole works by inhibiting the synthesis of ergosterol, an essential component of fungal cell membranes, thereby disrupting membrane integrity and leading to fungal cell death. It is indicated for the management of infections such as aspergillosis, blastomycosis, histoplasmosis, onychomycosis, and other dermatophytic infections. The capsule formulation ensures optimal bioavailability when administered orally, with absorption enhanced by concurrent intake of food. Itrez 100 Capsule is typically prescribed for adults and children above a certain age, with dosage and duration tailored according to the severity and type of infection. Caution is advised in patients with hepatic impairment or congestive heart failure, and periodic monitoring of liver function tests is recommended during prolonged therapy. Potential adverse effects include gastrointestinal disturbances, headache, rash, and, rarely, hepatotoxicity. Drug interactions may occur due to itraconazole’s inhibition of cytochrome P450 enzymes, necessitating careful review of concomitant medications. Itrez 100 Capsule should be used under medical supervision to ensure efficacy and minimize risks.