IT-Cure 100 Capsule contains Itraconazole 100 mg, a broad-spectrum antifungal agent belonging to the triazole class. It is indicated for the treatment of various fungal infections including aspergillosis, blastomycosis, histoplasmosis, and onychomycosis, as well as other systemic and superficial mycoses caused by susceptible fungi. Itraconazole exerts its antifungal effect by inhibiting the cytochrome P450-dependent enzyme lanosterol 14-α-demethylase, which is essential for the conversion of lanosterol to ergosterol, a key component of fungal cell membranes. This inhibition disrupts membrane synthesis, leading to increased membrane permeability and ultimately fungal cell death. IT-Cure 100 Capsule is administered orally and demonstrates good bioavailability, with absorption enhanced when taken with food. It is metabolized primarily in the liver via the CYP3A4 pathway and has a half-life of approximately 24-42 hours, allowing for once or twice daily dosing depending on the indication. Caution is advised in patients with hepatic impairment, and potential drug interactions should be carefully monitored due to its effect on cytochrome P450 enzymes. Common adverse effects include gastrointestinal disturbances, headache, and rash. IT-Cure 100 Capsule should be used under medical supervision to ensure appropriate dosing and monitoring.