Istaphase MG 2 Tablet PR
Istaphase MG 2 Tablet PR
Glimepiride (2mg) + Metformin (500mg) + Voglibose (0.2mg)
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About This Medicine
Product description & overview
Istaphase MG 2 Tablet PR is a combination oral antidiabetic medication containing Glimepiride 2 mg, Metformin 500 mg, and Voglibose 0.2 mg, designed for the management of type 2 diabetes mellitus. Glimepiride, a sulfonylurea class agent, stimulates pancreatic beta cells to enhance insulin secretion, thereby reducing blood glucose levels. Metformin, a biguanide, improves insulin sensitivity by decreasing hepatic glucose production and enhancing peripheral glucose uptake. Voglibose, an alpha-glucosidase inhibitor, delays carbohydrate absorption in the intestines, attenuating postprandial hyperglycemia. This triple combination targets multiple pathophysiological defects in type 2 diabetes, providing comprehensive glycemic control. Istaphase MG 2 Tablet PR is indicated for patients inadequately controlled on diet, exercise, and monotherapy or dual therapy with these agents. It should be administered with meals to minimize gastrointestinal side effects commonly associated with Metformin and Voglibose. Caution is advised in patients with renal or hepatic impairment, and regular monitoring of blood glucose, renal function, and liver enzymes is recommended. Hypoglycemia risk is increased due to Glimepiride; patients should be educated on recognizing and managing symptoms. This combination therapy offers a convenient and effective option for optimizing glycemic control in type 2 diabetes management.
Active composition
Glimepiride 2 mg
+2 more active ingredients
About Glimepiride
Glimepiride is an oral hypoglycemic agent used to manage blood sugar levels in patients with type 2 diabetes mellitus. It works by stimulating the pancreas to release more insulin, thereby lowering blood glucose levels and preventing the symptoms associated with diabetes. Glimepiride is often prescribed alongside diet and exercise to enhance glycemic control and reduce the risk of diabetes-related complications, such as kidney damage and neuropathy. In summary, Glimepiride is an essential medication for controlling blood sugar levels in type 2 diabetes patients.
How It Works
Glimepiride stimulates insulin secretion from pancreatic beta cells and enhances insulin sensitivity in peripheral tissues, facilitating glucose uptake and lowering blood sugar levels.
All Active Ingredients
Voglibose
Voglibose inhibits intestinal alpha-glucosidases, delaying carbohydrate digestion and absorption, thus lowering postprandial glucose levels.
Metformin
Metformin reduces hepatic glucose production and enhances peripheral insulin sensitivity, lowering blood glucose levels.
Dosage & How to Use
Dosage information not available. Please consult your doctor or pharmacist.
Safety Advice
Important precautions
Side Effect Occurrence
Based on clinical trials and patient reports.
Overall Tolerance
Most patients tolerate well
Common Side Effects
Safety Advice
Alcohol
It is unsafe to consume alcohol with Istaphase MG 2 Tablet PR.
High Risk
Driving
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
Exercise Caution
Liver
Istaphase MG 2 Tablet PR should be used with caution in patients with liver disease. Dose adjustment of Istaphase MG 2 Tablet PR may be needed. Please consult your doctor. Istaphase MG 2 Tablet PR is generally started with low dose in patients with mild to moderate liver disease and its use is not recommended in patients with severe liver disease.
Regular Checkup
Breastfeeding
Istaphase MG 2 Tablet PR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Consult Doctor
Kidney
Istaphase MG 2 Tablet PR is probably unsafe to use in patients with kidney disease and should be avoided. Please consult your doctor. Use of Istaphase MG 2 Tablet PR is, however, not recommended in patients with severe kidney disease.
Regular Checkup
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