Isogaba M Tablet is a combination medication containing Methylcobalamin 1500 mcg and Pregabalin 75 mg, primarily indicated for the management of neuropathic pain and related neurological disorders. Methylcobalamin, an active form of vitamin B12, plays a crucial role in nerve regeneration, myelin sheath repair, and overall neuronal health, thereby aiding in the recovery of nerve damage and improving nerve conduction. Pregabalin, a gamma-aminobutyric acid (GABA) analog, exerts its therapeutic effect by modulating calcium channel function in the central nervous system, leading to a reduction in neurotransmitter release and attenuation of neuropathic pain signals. This combination is particularly effective in conditions such as diabetic peripheral neuropathy, postherpetic neuralgia, and other neuropathic pain syndromes. Isogaba M Tablet may also be used as adjunctive therapy in epilepsy and generalized anxiety disorder as prescribed by a healthcare professional. The medication should be taken under medical supervision, with dosage adjustments based on clinical response and tolerability. Common side effects may include dizziness, somnolence, and gastrointestinal disturbances. Caution is advised in patients with renal impairment, and it is contraindicated in individuals with known hypersensitivity to either component. Regular monitoring and adherence to prescribed dosage enhance therapeutic outcomes and minimize adverse effects.