Ismet 500mg Tablet contains Metformin hydrochloride, a biguanide antihyperglycemic agent used primarily in the management of type 2 diabetes mellitus. It functions by decreasing hepatic glucose production, decreasing intestinal absorption of glucose, and improving insulin sensitivity by increasing peripheral glucose uptake and utilization. Ismet 500mg is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes. It may be used as monotherapy or in combination with other antidiabetic agents, including insulin. The tablet should be administered orally, typically starting with a low dose to minimize gastrointestinal side effects such as nausea, vomiting, diarrhea, and abdominal discomfort, which are the most common adverse reactions. Metformin is contraindicated in patients with renal impairment, metabolic acidosis, or hypersensitivity to the drug. Regular monitoring of renal function and blood glucose levels is recommended during therapy. Unlike some antidiabetic medications, Metformin does not cause hypoglycemia when used alone. It is also associated with modest weight loss or weight neutrality, making it a preferred agent in overweight diabetic patients. Proper adherence to prescribed dosage and lifestyle modifications is essential for optimal therapeutic outcomes with Ismet 500mg Tablet.