Ishinac-SP Tablet is a combination analgesic and anti-inflammatory medication containing Aceclofenac 100 mg, Paracetamol 325 mg, and Serratiopeptidase 15 mg. Aceclofenac, a non-steroidal anti-inflammatory drug (NSAID), provides potent anti-inflammatory and analgesic effects by inhibiting cyclooxygenase enzymes, thereby reducing prostaglandin synthesis. Paracetamol contributes effective analgesic and antipyretic properties, enhancing pain relief and fever reduction without significant anti-inflammatory activity. Serratiopeptidase, a proteolytic enzyme, facilitates the breakdown of inflammatory mediators and promotes the resolution of edema and tissue inflammation. The synergistic action of these three components makes Ishinac-SP effective in managing acute and chronic musculoskeletal pain, postoperative pain, dental pain, and inflammatory conditions such as arthritis. This combination is particularly useful in conditions where inflammation and pain coexist, providing rapid symptom relief while minimizing the need for higher doses of individual drugs, potentially reducing adverse effects. Ishinac-SP should be used under medical supervision, with caution advised in patients with gastrointestinal ulcers, hepatic or renal impairment, and hypersensitivity to NSAIDs or any component of the formulation. Regular monitoring is recommended during prolonged therapy to ensure safety and efficacy.