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Iritero 100 Injection

Iritero 100 Injection

Irinotecan (20mg/ml)

Hetero Drugs Ltd
anti-cancer
957.601197.0020% OFF
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About This Medicine

Product description & overview

Iritero 100 Injection contains Irinotecan at a concentration of 20 mg/ml and is indicated for the treatment of metastatic colorectal cancer and other solid tumors as determined by clinical assessment. Irinotecan is a topoisomerase I inhibitor that interferes with DNA replication by stabilizing the cleavable complex formed between topoisomerase I and DNA, leading to DNA strand breaks and apoptosis in rapidly dividing cancer cells. Administered intravenously, Iritero 100 Injection is typically used as a single agent or in combination with other chemotherapeutic regimens such as fluorouracil and leucovorin. Dosage and administration should be individualized based on patient tolerance, prior therapy, and hematologic parameters. Common adverse effects include neutropenia, diarrhea, nausea, vomiting, and fatigue, necessitating close monitoring of blood counts and supportive care measures. Premedication with antiemetics and atropine may be required to manage cholinergic symptoms and gastrointestinal side effects. Iritero 100 Injection is contraindicated in patients with known hypersensitivity to irinotecan or its components and should be used cautiously in individuals with hepatic impairment. Proper dilution and infusion protocols must be followed to ensure safety and efficacy. This medication should be prescribed and administered by healthcare professionals experienced in chemotherapy management.

Active composition

Irinotecan

About Irinotecan

Irinotecan is an antineoplastic agent used primarily in the treatment of colorectal cancer. This chemotherapy drug works by inhibiting topoisomerase I, an enzyme essential for DNA replication and cell division. By blocking this enzyme, Irinotecan prevents cancer cells from multiplying, thereby inhibiting tumor growth. It is typically administered in a clinical setting under the supervision of healthcare professionals. Common side effects may include nausea, diarrhea, and fatigue. In summary, Irinotecan is a critical component in the management of colorectal cancer.

How It Works

Irinotecan exerts its anticancer effects by inhibiting topoisomerase I, preventing DNA replication and leading to the death of rapidly dividing cancer cells.

Dosage & How to Use

Dosage information not available. Please consult your doctor or pharmacist.

Safety Advice

Important precautions

Side Effect Occurrence

Based on clinical trials and patient reports.

Overall Tolerance

Most patients tolerate well

Only 2.3% reported effects

Common Side Effects

Headache8%
Nausea5%
Dizziness3%
Fatigue2%
Rash1%
Higher
Lower

Safety Advice

Alcohol

It is not known whether it is safe to consume alcohol with Iritero 100 Injection. Please consult your doctor.

High Risk

Driving

Iritero 100 Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Exercise Caution

Liver

There is limited information available on the use of Iritero 100 Injection in patients with liver disease. Please consult your doctor.

Regular Checkup

Breastfeeding

Iritero 100 Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Consult Doctor

Kidney

Iritero 100 Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Iritero 100 Injection may not be needed in these patients. Please consult your doctor. Use of this medicine is not recommended for patients on dialysis.

Regular Checkup

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