IrinoSym 100 Injection
IrinoSym 100 Injection
Irinotecan (20mg/ml)
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About This Medicine
Product description & overview
IrinoSym 100 Injection contains Irinotecan at a concentration of 20 mg/ml and is indicated for the treatment of metastatic colorectal cancer and other malignancies as determined by clinical evaluation. Irinotecan is a topoisomerase I inhibitor that interferes with DNA replication and transcription, leading to apoptosis of rapidly dividing cancer cells. The injection is administered intravenously under the supervision of an oncology specialist, with dosage and schedule tailored to the patient’s clinical condition, prior treatment history, and tolerance. Common adverse effects include neutropenia, diarrhea, nausea, vomiting, and fatigue, necessitating careful monitoring of hematologic parameters and supportive care measures. Hypersensitivity reactions may occur, and premedication with antiemetics and atropine is recommended to mitigate cholinergic symptoms. IrinoSym 100 Injection should be used with caution in patients with hepatic impairment or pre-existing gastrointestinal disorders. It is contraindicated in patients with known hypersensitivity to irinotecan or any component of the formulation. Due to its cytotoxic nature, appropriate handling and disposal procedures must be followed to prevent exposure to healthcare personnel. IrinoSym 100 Injection is a critical component in combination chemotherapy regimens aimed at improving survival and quality of life in patients with advanced malignancies.
Active composition
Irinotecan
About Irinotecan
Irinotecan is an antineoplastic agent used primarily in the treatment of colorectal cancer. This chemotherapy drug works by inhibiting topoisomerase I, an enzyme essential for DNA replication and cell division. By blocking this enzyme, Irinotecan prevents cancer cells from multiplying, thereby inhibiting tumor growth. It is typically administered in a clinical setting under the supervision of healthcare professionals. Common side effects may include nausea, diarrhea, and fatigue. In summary, Irinotecan is a critical component in the management of colorectal cancer.
How It Works
Irinotecan exerts its anticancer effects by inhibiting topoisomerase I, preventing DNA replication and leading to the death of rapidly dividing cancer cells.
Dosage & How to Use
Dosage information not available. Please consult your doctor or pharmacist.
Safety Advice
Important precautions
Side Effect Occurrence
Based on clinical trials and patient reports.
Overall Tolerance
Most patients tolerate well
Common Side Effects
Safety Advice
Alcohol
It is not known whether it is safe to consume alcohol with IrinoSym 100 Injection. Please consult your doctor.
High Risk
Driving
IrinoSym 100 Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Liver
There is limited information available on the use of IrinoSym 100 Injection in patients with liver disease. Please consult your doctor.
Regular Checkup
Breastfeeding
IrinoSym 100 Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Consult Doctor
Kidney
IrinoSym 100 Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of IrinoSym 100 Injection may not be needed in these patients. Please consult your doctor. Use of this medicine is not recommended for patients on dialysis.
Regular Checkup
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