Intrazole 100 Capsule contains Itraconazole 100 mg, a broad-spectrum antifungal agent belonging to the triazole class. It is indicated for the treatment of various fungal infections including aspergillosis, blastomycosis, histoplasmosis, and onychomycosis, as well as other systemic and superficial mycoses caused by susceptible fungi. Itraconazole works by inhibiting the synthesis of ergosterol, an essential component of fungal cell membranes, thereby disrupting cell membrane integrity and leading to fungal cell death. Intrazole 100 Capsule is administered orally and exhibits good bioavailability when taken with food, enhancing absorption. The drug is metabolized primarily in the liver via the cytochrome P450 system, necessitating caution in patients with hepatic impairment and potential drug interactions. Common adverse effects include gastrointestinal disturbances such as nausea, vomiting, and abdominal pain, as well as headache and dizziness. Rare but serious side effects may include hepatotoxicity and congestive heart failure exacerbation. Intrazole 100 Capsule should be used under medical supervision, with appropriate monitoring of liver function tests and clinical response. It is contraindicated in patients with known hypersensitivity to itraconazole or other azole antifungals. Dose adjustments may be required based on the severity of infection and patient-specific factors.