Intoxib 90 Tablet contains Etoricoxib 90 mg, a selective cyclooxygenase-2 (COX-2) inhibitor indicated for the management of pain and inflammation associated with various musculoskeletal disorders. Etoricoxib exerts its therapeutic effect by selectively inhibiting the COX-2 enzyme, thereby reducing the synthesis of prostaglandins responsible for inflammation, pain, and fever, while sparing COX-1 activity, which helps minimize gastrointestinal adverse effects commonly seen with non-selective NSAIDs. Intoxib 90 is primarily prescribed for conditions such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and acute gouty arthritis. It is also effective in managing chronic musculoskeletal pain and postoperative dental pain. The recommended dosage should be individualized based on the severity of the condition and patient response, with caution advised in patients with cardiovascular risk factors, renal or hepatic impairment. Common side effects may include headache, dizziness, hypertension, and gastrointestinal discomfort, although the incidence of serious gastrointestinal complications is lower compared to traditional NSAIDs. Intoxib 90 should be used under medical supervision, particularly in patients with a history of cardiovascular disease or gastrointestinal ulcers. Regular monitoring is recommended during prolonged therapy to ensure safety and efficacy.