Inderal F 10 Tablet SR is a sustained-release formulation combining Propranolol 40 mg and Flunarizine 10 mg, designed for the management of various cardiovascular and neurological conditions. Propranolol, a non-selective beta-adrenergic blocker, exerts its therapeutic effects by reducing heart rate, myocardial contractility, and cardiac output, thereby lowering blood pressure and preventing angina pectoris. It is also effective in the prophylaxis of migraine and the treatment of certain arrhythmias. Flunarizine, a calcium channel blocker with antihistaminic properties, is primarily used for migraine prophylaxis and to alleviate vertigo by inhibiting calcium influx into vascular smooth muscle and neurons, stabilizing vascular tone and neuronal excitability. The combination in Inderal F 10 Tablet SR offers synergistic benefits in migraine prevention and cardiovascular protection, improving patient compliance through once-daily sustained-release dosing. It is indicated for patients requiring both beta-blockade and calcium channel inhibition, particularly those with coexisting hypertension, angina, migraine, or vestibular disorders. Caution is advised in patients with asthma, bradycardia, or hepatic impairment. Common adverse effects include fatigue, dizziness, and gastrointestinal disturbances. Inderal F 10 Tablet SR should be used under medical supervision with regular monitoring of cardiovascular status.