Hyphoral Tablet contains Ketoconazole 200 mg, an antifungal agent belonging to the imidazole class, indicated for the treatment of various systemic and superficial fungal infections. Ketoconazole exerts its effect by inhibiting the synthesis of ergosterol, an essential component of fungal cell membranes, thereby disrupting membrane integrity and leading to fungal cell death. Hyphoral is effective against dermatophytes, yeasts, and some pathogenic fungi responsible for conditions such as candidiasis, tinea infections, and seborrheic dermatitis. This oral formulation is typically prescribed when topical therapy is inadequate or impractical. Administration should be under medical supervision, with dosage and duration tailored according to the severity and type of infection. Common adverse effects include gastrointestinal disturbances such as nausea, vomiting, and abdominal pain, as well as potential hepatotoxicity; therefore, liver function monitoring is recommended during prolonged therapy. Caution is advised in patients with pre-existing liver disease or those taking medications metabolized via the cytochrome P450 system due to possible drug interactions. Hyphoral Tablet should be used with caution in pregnancy and lactation, and only when the potential benefits outweigh the risks. Proper adherence to prescribed dosing is essential to prevent resistance and ensure therapeutic efficacy.