Hypernil 5mg Tablet contains Lisinopril, an angiotensin-converting enzyme (ACE) inhibitor primarily indicated for the management of hypertension and heart failure. By inhibiting the ACE enzyme, Lisinopril reduces the conversion of angiotensin I to angiotensin II, a potent vasoconstrictor, thereby promoting vasodilation and lowering blood pressure. This mechanism also decreases aldosterone secretion, leading to reduced sodium and water retention, which helps alleviate cardiac workload. Hypernil 5mg is commonly prescribed to control high blood pressure, reducing the risk of stroke, myocardial infarction, and renal complications. Additionally, it is effective in improving survival rates post-myocardial infarction and managing symptomatic heart failure. The recommended dosage should be individualized based on patient response and clinical condition, with regular monitoring of blood pressure, renal function, and serum electrolytes advised during therapy. Common adverse effects include cough, dizziness, headache, and hyperkalemia. Caution is warranted in patients with renal impairment, bilateral renal artery stenosis, or history of angioedema. Hypernil 5mg should not be used during pregnancy due to potential fetal toxicity. Patients are advised to adhere strictly to prescribed dosages and consult healthcare providers before initiating or discontinuing therapy.