Histiol 16 Tablet contains Betahistine 16 mg, an active pharmaceutical ingredient primarily indicated for the treatment of vertigo associated with Ménière’s disease and other vestibular disorders. Betahistine acts as a histamine analogue, exerting its therapeutic effect by improving microcirculation in the inner ear and reducing the pressure caused by endolymphatic hydrops. This mechanism helps alleviate symptoms such as dizziness, tinnitus, hearing loss, and nausea. Histiol 16 is administered orally and is generally well tolerated. The recommended dosage varies depending on the severity of the condition and the patient’s response, typically starting with 16 mg two to three times daily. Betahistine is contraindicated in patients with pheochromocytoma and should be used cautiously in individuals with a history of peptic ulcers or asthma. Common adverse effects are mild and may include gastrointestinal discomfort, headache, and allergic reactions. It is essential to follow the prescribing physician’s instructions and avoid abrupt discontinuation to prevent symptom recurrence. Histiol 16 Tablet should be stored in a cool, dry place, away from direct sunlight and out of reach of children. Consultation with a healthcare professional is advised before initiating therapy to ensure appropriate use and monitoring.