Hista 3G Tablet is a combination medication containing Montelukast 10 mg and Fexofenadine 120 mg, formulated for the effective management of allergic conditions. Montelukast, a leukotriene receptor antagonist, works by blocking substances called leukotrienes that cause inflammation, bronchoconstriction, and mucus production, thereby providing relief from symptoms associated with asthma and allergic rhinitis. Fexofenadine, a second-generation antihistamine, selectively inhibits peripheral H1 receptors, reducing the effects of histamine and alleviating symptoms such as sneezing, runny nose, itchy or watery eyes, and urticaria. The synergistic action of these two agents makes Hista 3G Tablet particularly useful in treating seasonal allergic rhinitis, chronic idiopathic urticaria, and other allergic manifestations where both histamine and leukotrienes play a role. The tablet is generally well tolerated, with a low incidence of sedation due to the non-sedating properties of Fexofenadine. It is recommended for use under medical supervision, especially in patients with a history of hypersensitivity to either component or with underlying hepatic or renal impairment. Hista 3G provides a convenient and effective option for comprehensive allergy symptom control, improving patient quality of life through dual-action pharmacotherapy.