Hifenac-D Tablet is a combination analgesic and anti-inflammatory medication containing Aceclofenac 100 mg, Paracetamol 325 mg, and Serratiopeptidase 15 mg. Aceclofenac, a non-steroidal anti-inflammatory drug (NSAID), provides effective relief from pain and inflammation by inhibiting cyclooxygenase enzymes, thereby reducing prostaglandin synthesis. Paracetamol acts as an analgesic and antipyretic, offering symptomatic relief from mild to moderate pain and fever through central inhibition of prostaglandin synthesis. Serratiopeptidase, a proteolytic enzyme, facilitates the reduction of inflammation and edema by breaking down inflammatory mediators and promoting tissue repair. The combined action of these three components makes Hifenac-D suitable for managing acute musculoskeletal conditions such as arthritis, tendonitis, bursitis, postoperative pain, and soft tissue injuries. It is particularly beneficial in reducing pain, swelling, and stiffness associated with inflammatory disorders. Hifenac-D should be used under medical supervision, with caution advised in patients with gastrointestinal ulcers, hepatic or renal impairment, and hypersensitivity to any component. It is contraindicated in patients with bleeding disorders or those on anticoagulant therapy. Adverse effects may include gastrointestinal discomfort, allergic reactions, and rare instances of hepatic dysfunction. Proper dosage and duration should be adhered to in order to minimize risks and optimize therapeutic outcomes.