Heptral 400mg Tablet contains Ademetionine 400mg, a naturally occurring compound involved in methylation processes and hepatic function. It is primarily indicated for the treatment of liver disorders, including cholestasis, intrahepatic cholestasis, and liver cirrhosis, as well as for the management of depressive disorders associated with hepatic dysfunction. Ademetionine acts by restoring normal liver cell membrane fluidity and enhancing the synthesis of glutathione, a key antioxidant that protects hepatocytes from oxidative stress and promotes detoxification. Additionally, it supports the regeneration of liver cells and improves bile flow, thereby aiding in the resolution of cholestasis. Heptral is also recognized for its neuroprotective and mood-enhancing properties, attributed to its role in neurotransmitter synthesis, making it beneficial in depressive states linked to liver disease. The recommended dosage and duration of treatment should be individualized based on the severity of the condition and patient response, under medical supervision. Common adverse effects are generally mild and may include gastrointestinal disturbances such as nausea or abdominal discomfort. Heptral 400mg Tablet should be used cautiously in patients with bipolar disorder or those receiving antidepressant therapy. It is contraindicated in individuals with hypersensitivity to Ademetionine or any tablet components.