Hepdine Syrup is a combination pharmaceutical formulation containing Cyproheptadine hydrochloride (2mg/5ml) and Tricholine Citrate (275mg/5ml), designed to provide antihistaminic and hepatoprotective benefits. Cyproheptadine, a first-generation antihistamine, exhibits potent antiserotonergic and anticholinergic properties, making it effective in the management of allergic conditions such as rhinitis, urticaria, and pruritus. It also stimulates appetite, which can be beneficial in patients experiencing anorexia or weight loss. Tricholine Citrate acts as a choleretic agent, promoting bile secretion and supporting liver function, thereby aiding in the detoxification process and improving metabolic activities associated with hepatic insufficiency. Hepdine Syrup is indicated for symptomatic relief in allergic disorders accompanied by hepatic dysfunction or compromised appetite. The syrup formulation ensures ease of administration, particularly in pediatric and geriatric populations. Dosage and duration of therapy should be determined by a healthcare professional based on individual patient needs and clinical response. Caution is advised in patients with a history of glaucoma, peptic ulcer, or urinary retention due to the anticholinergic effects of Cyproheptadine. Hepdine Syrup should be used under medical supervision to optimize therapeutic outcomes and minimize potential adverse effects.