Harmoni-F Tablet is a combination oral contraceptive containing Cyproterone acetate (2mg), Ethinyl Estradiol (0.035mg), and Folic Acid (5mg). Cyproterone acetate is a synthetic progestogen with anti-androgenic properties, effectively reducing androgen-related symptoms such as acne and hirsutism. Ethinyl Estradiol is a potent synthetic estrogen that works synergistically with Cyproterone acetate to inhibit ovulation, alter cervical mucus, and modify the endometrial lining, thereby providing reliable contraception. The inclusion of Folic Acid at 5mg supports folate levels, which is essential for DNA synthesis and cellular division, and is particularly beneficial in women planning pregnancy after discontinuation of the contraceptive to reduce the risk of neural tube defects in the fetus. Harmoni-F is indicated for the treatment of androgen-dependent conditions in women, such as moderate to severe acne and hirsutism, as well as for contraception. It should be used under medical supervision, considering contraindications such as thromboembolic disorders, liver disease, and hormone-sensitive malignancies. Regular monitoring is advised to assess tolerance and efficacy. Patients should be counseled on adherence, potential side effects, and the importance of folic acid supplementation for reproductive health.