Halox S Lotion is a topical dermatological formulation containing Halobetasol propionate (0.05% w/v) and Salicylic Acid (3% w/v), indicated for the treatment of various inflammatory and hyperkeratotic skin conditions. Halobetasol propionate, a potent corticosteroid, exerts strong anti-inflammatory, antipruritic, and vasoconstrictive effects, effectively reducing erythema, swelling, and itching associated with dermatoses such as psoriasis, eczema, and lichen planus. Salicylic Acid, a keratolytic agent, facilitates the removal of scales and promotes desquamation by softening and loosening keratin, thereby enhancing the penetration and efficacy of the corticosteroid component. Halox S Lotion is particularly beneficial in managing thick, scaly plaques and hyperkeratotic lesions. The combination therapy allows for rapid symptomatic relief and improved skin appearance. It should be applied topically to the affected area once or twice daily, as directed by a healthcare professional, avoiding contact with eyes, mucous membranes, and broken skin. Prolonged use or application over large areas should be avoided due to potential systemic absorption and side effects associated with potent corticosteroids. Contraindications include hypersensitivity to any component, untreated bacterial, viral, or fungal skin infections. Use during pregnancy and lactation should be under medical supervision.