Gynaset-CR 15 Tablet contains Norethisterone 15 mg, a synthetic progestogen used primarily for the management of menstrual disorders and gynecological conditions related to progesterone deficiency. Norethisterone exerts its therapeutic effects by mimicking the natural hormone progesterone, thereby regulating the menstrual cycle and stabilizing the endometrium. This medication is indicated for the treatment of irregular menstruation, secondary amenorrhea, dysmenorrhea, and endometriosis. It is also utilized for delaying menstruation when necessary. Gynaset-CR 15 is administered orally, with dosage and duration tailored according to the specific clinical condition and patient response. The drug’s mechanism involves suppression of the hypothalamic-pituitary-ovarian axis, leading to inhibition of ovulation and modulation of endometrial growth. Common side effects may include nausea, headache, breast tenderness, and changes in menstrual bleeding patterns. Contraindications include known hypersensitivity to norethisterone or other progestogens, active thromboembolic disorders, liver disease, and hormone-dependent malignancies. Caution is advised in patients with cardiovascular risk factors, hypertension, or a history of depression. Gynaset-CR 15 should be used under medical supervision, with periodic monitoring to ensure efficacy and safety.