Gudnerv-NT Tablet SR is a sustained-release formulation combining Pregabalin 75mg, Nortriptyline 10mg, and Methylcobalamin 1500mcg, designed for the management of neuropathic pain and associated conditions. Pregabalin, a gamma-aminobutyric acid (GABA) analogue, acts by modulating calcium channels to reduce neurotransmitter release, thereby alleviating neuropathic pain and seizures. Nortriptyline, a tricyclic antidepressant, enhances noradrenergic and serotonergic neurotransmission, contributing to its analgesic and mood-stabilizing effects, particularly beneficial in chronic neuropathic pain syndromes. Methylcobalamin, an active form of vitamin B12, supports nerve regeneration and repair by promoting myelin sheath synthesis and neuronal function. The combination therapy targets multiple pathways involved in neuropathic pain, providing symptomatic relief and improving nerve health. Gudnerv-NT Tablet SR is indicated for diabetic neuropathy, postherpetic neuralgia, peripheral neuropathy, and other neuropathic pain disorders. It should be used under medical supervision, with dosage adjustments based on clinical response and tolerability. Common adverse effects may include dizziness, somnolence, dry mouth, and gastrointestinal disturbances. Caution is advised in patients with renal impairment, cardiac conditions, or those on concomitant central nervous system depressants. Regular monitoring is recommended to optimize therapeutic outcomes and minimize side effects.