Grisure 500mg Tablet contains Griseofulvin, an antifungal agent effective in the treatment of dermatophytic infections of the skin, hair, and nails. It is primarily indicated for conditions such as tinea corporis, tinea cruris, tinea pedis, and onychomycosis caused by susceptible strains of dermatophytes. Griseofulvin acts by inhibiting fungal cell mitosis through disruption of microtubule function, thereby preventing fungal growth and replication. The drug is administered orally and is absorbed better when taken with fatty meals, enhancing its bioavailability. Dosage and duration of therapy depend on the severity and location of the infection, typically ranging from several weeks to months to ensure complete eradication and prevent recurrence. Common side effects may include headache, gastrointestinal disturbances such as nausea and diarrhea, and photosensitivity reactions. It is contraindicated in patients with hypersensitivity to Griseofulvin, porphyria, or severe liver impairment. Caution is advised in pregnant or breastfeeding women. Regular monitoring of liver function and blood counts may be recommended during prolonged therapy. Grisure 500mg Tablet should be used under medical supervision to ensure appropriate use and to minimize the risk of resistance and adverse effects.