Gluconorm-VG 2 Forte Tablet SR is a combination oral hypoglycemic agent formulated to improve glycemic control in patients with type 2 diabetes mellitus. It contains Glimepiride (2mg), Metformin (1000mg), and Voglibose (0.2mg), each contributing distinct mechanisms to regulate blood glucose levels effectively. Glimepiride, a sulfonylurea, stimulates pancreatic beta cells to increase insulin secretion, thereby reducing blood glucose. Metformin, a biguanide, primarily decreases hepatic glucose production and enhances peripheral glucose uptake and utilization, improving insulin sensitivity. Voglibose, an alpha-glucosidase inhibitor, delays carbohydrate absorption from the intestine, leading to a reduction in postprandial hyperglycemia. The sustained-release formulation ensures a gradual release of active ingredients, promoting stable plasma drug concentrations and minimizing gastrointestinal side effects commonly associated with metformin and voglibose. Gluconorm-VG 2 Forte is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes inadequately controlled by monotherapy or dual therapy. It should be used under medical supervision, with regular monitoring of blood glucose levels and renal function. Caution is advised in patients with hepatic or renal impairment, and it is contraindicated in cases of diabetic ketoacidosis or severe infections.