Gluconorm P 15 Tablet ER
Gluconorm P 15 Tablet ER
Pioglitazone (15mg) + Metformin (500mg)
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About This Medicine
Product description & overview
Gluconorm P 15 Tablet ER is a combination oral antidiabetic medication containing Pioglitazone 15 mg and Metformin 500 mg extended-release. It is primarily indicated for the management of type 2 diabetes mellitus in patients who are inadequately controlled on diet and exercise alone or those already receiving monotherapy with either component. Pioglitazone, a thiazolidinedione, improves insulin sensitivity by activating peroxisome proliferator-activated receptor gamma (PPAR-γ), thereby enhancing peripheral glucose uptake and utilization. Metformin, a biguanide, decreases hepatic glucose production and improves insulin sensitivity, contributing to better glycemic control. The extended-release formulation allows for once-daily dosing, promoting patient compliance and minimizing gastrointestinal side effects commonly associated with immediate-release metformin. Gluconorm P 15 Tablet ER should be used as part of a comprehensive diabetes management plan including diet, exercise, and regular monitoring of blood glucose levels. Caution is advised in patients with renal impairment, hepatic dysfunction, or congestive heart failure. Common adverse effects may include gastrointestinal disturbances, edema, and weight gain. Regular monitoring of liver function and renal parameters is recommended during therapy. This combination offers a synergistic approach to glycemic control, improving both fasting and postprandial blood glucose levels effectively.
Active composition
Metformin 500 mg
+1 more active ingredient
About Metformin
Metformin is an oral antihyperglycemic agent used to manage type 2 diabetes mellitus. It works by decreasing glucose production in the liver and improving insulin sensitivity. Metformin is effective in controlling blood sugar levels and preventing diabetes-related complications. In summary, Metformin is vital for managing type 2 diabetes.
How It Works
Metformin reduces hepatic glucose production and enhances peripheral insulin sensitivity, lowering blood glucose levels.
All Active Ingredients
Pioglitazone
Pioglitazone activates peroxisome proliferator-activated receptor gamma (PPAR-γ), enhancing insulin sensitivity and glucose metabolism.
Dosage & How to Use
Dosage information not available. Please consult your doctor or pharmacist.
Safety Advice
Important precautions
Side Effect Occurrence
Based on clinical trials and patient reports.
Overall Tolerance
Most patients tolerate well
Common Side Effects
Safety Advice
Alcohol
Gluconorm P 15 Tablet ER may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
High Risk
Pregnancy
Gluconorm P 15 Tablet ER is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Medical Advice
Driving
Gluconorm P 15 Tablet ER should be used with caution in patients with kidney disease. Dose adjustment of Gluconorm P 15 Tablet ER may be needed. Please consult your doctor. Use of Gluconorm P 15 Tablet ER is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.
Exercise Caution
Breastfeeding
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
Consult Doctor
Kidney
Gluconorm P 15 Tablet ER should be used with caution in patients with liver disease. Dose adjustment of Gluconorm P 15 Tablet ER may be needed. Please consult your doctor. Gluconorm P 15 Tablet ER is generally started with low dose in patients with mild to moderate liver disease and its use is not recommended in patients with severe liver disease.
Regular Checkup
Customer Reviews
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