Glizihenz-M-80 Tablet

Glizihenz-M-80 Tablet
Gliclazide (80mg) + Metformin (500mg)
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About This Medicine
Product description & overview
Glizihenz-M-80 Tablet is a combination oral hypoglycemic agent containing Gliclazide 80 mg and Metformin 500 mg, indicated for the management of type 2 diabetes mellitus. Gliclazide, a sulfonylurea class drug, enhances pancreatic insulin secretion, thereby improving glycemic control. Metformin, a biguanide, primarily decreases hepatic glucose production and increases peripheral insulin sensitivity, contributing to improved glucose uptake and utilization. The synergistic action of these two agents addresses multiple pathophysiological defects in type 2 diabetes, facilitating better blood glucose regulation. Glizihenz-M-80 is recommended as an adjunct to diet and exercise to improve glycemic control in patients inadequately controlled on monotherapy or lifestyle modifications alone. It is essential to monitor blood glucose levels regularly to adjust dosage and minimize the risk of hypoglycemia, particularly due to the sulfonylurea component. Caution is advised in patients with renal impairment, hepatic dysfunction, or cardiovascular disease. Common adverse effects may include gastrointestinal disturbances, hypoglycemia, and, rarely, lactic acidosis associated with Metformin use. Patient education on adherence, diet, and symptom recognition is crucial for optimal therapeutic outcomes. Glizihenz-M-80 should be prescribed under medical supervision with periodic assessment of renal function and glycemic status.
Active composition
Metformin 500 mg
+1 more active ingredient
About Metformin
Metformin is an oral antihyperglycemic agent used to manage type 2 diabetes mellitus. It works by decreasing glucose production in the liver and improving insulin sensitivity. Metformin is effective in controlling blood sugar levels and preventing diabetes-related complications. In summary, Metformin is vital for managing type 2 diabetes.
How It Works
Metformin reduces hepatic glucose production and enhances peripheral insulin sensitivity, lowering blood glucose levels.
All Active Ingredients
Gliclazide
Gliclazide stimulates insulin secretion from pancreatic beta cells and enhances insulin sensitivity in peripheral tissues.
Dosage & How to Use
Dosage information not available. Please consult your doctor or pharmacist.
Safety Advice
Important precautions
Side Effect Occurrence
Based on clinical trials and patient reports.
Overall Tolerance
Most patients tolerate well
Common Side Effects
Safety Advice
Alcohol
It is unsafe to consume alcohol with Glizihenz-M-80 Tablet.
High Risk
Pregnancy
Glizihenz-M-80 Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Medical Advice
Driving
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
Exercise Caution
Liver
Glizihenz-M-80 Tablet should be used with caution in patients with liver disease. Dose adjustment of Glizihenz-M-80 Tablet may be needed. Please consult your doctor. Glizihenz-M-80 Tablet is generally started with low dose in patients with mild to moderate liver disease and its use is not recommended in patients with severe liver disease.
Regular Checkup
Breastfeeding
Glizihenz-M-80 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Consult Doctor
Kidney
Glizihenz-M-80 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Glizihenz-M-80 Tablet may be needed. Please consult your doctor. Use of Glizihenz-M-80 Tablet is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.
Regular Checkup
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