Gestofit 400 Soft Gelatin Capsule contains Progesterone 400 mg, a naturally occurring steroid hormone essential for regulating the menstrual cycle and maintaining pregnancy. This medication is primarily indicated for hormone replacement therapy in conditions associated with progesterone deficiency, such as amenorrhea, abnormal uterine bleeding due to hormonal imbalance, and luteal phase support in assisted reproductive technology. Progesterone acts by preparing the endometrium for implantation and maintaining the uterine lining during early pregnancy. Gestofit 400 is administered orally or vaginally, depending on the clinical indication and physician’s recommendation. It is contraindicated in patients with known hypersensitivity to progesterone or any component of the formulation, undiagnosed vaginal bleeding, active thrombophlebitis, or history of thromboembolic disorders. Common adverse effects may include dizziness, headache, breast tenderness, and gastrointestinal disturbances. Caution is advised in patients with hepatic impairment, cardiovascular disease, or a history of hormone-sensitive malignancies. Regular monitoring by a healthcare professional is recommended to assess therapeutic response and detect any potential adverse reactions. Gestofit 400 should be used under medical supervision, adhering strictly to prescribed dosage and duration to ensure efficacy and safety.