Gestmate SR 200 Tablet contains Progesterone 200 mg, a naturally occurring steroid hormone essential for the regulation of the menstrual cycle and maintenance of pregnancy. This sustained-release formulation ensures a gradual and consistent release of progesterone, optimizing therapeutic efficacy and minimizing dosing frequency. Gestmate SR 200 is primarily indicated for the treatment of progesterone deficiency states, including luteal phase support in assisted reproductive technology (ART) protocols, prevention of threatened miscarriage, and management of menstrual disorders such as irregular menstruation or secondary amenorrhea. Additionally, it may be used in hormone replacement therapy to counteract estrogen-induced endometrial hyperplasia. Progesterone acts by preparing the endometrium for implantation, maintaining uterine quiescence during pregnancy, and modulating the immune response to support fetal development. The tablet should be administered as prescribed by a healthcare professional, with dosage tailored to the specific clinical condition. Common side effects may include mild dizziness, headache, breast tenderness, and gastrointestinal discomfort. Caution is advised in patients with a history of thromboembolic disorders, hepatic impairment, or hypersensitivity to progesterone. Regular monitoring and follow-up are recommended to assess therapeutic response and detect any adverse effects. Gestmate SR 200 Tablet should be stored in a cool, dry place away from direct sunlight.