Gestate SR 300 Tablet contains natural micronized progesterone 300 mg and is indicated for use in various gynecological and obstetric conditions requiring progesterone supplementation. Progesterone is a naturally occurring hormone essential for the regulation of the menstrual cycle, maintenance of pregnancy, and preparation of the endometrium for implantation. Gestate SR 300 is commonly prescribed in cases of luteal phase deficiency, prevention of threatened or recurrent miscarriage, and support of assisted reproductive technologies such as in vitro fertilization (IVF). The sustained-release formulation ensures a prolonged therapeutic effect, maintaining stable progesterone levels over an extended period, thereby enhancing patient compliance and efficacy. This medication should be used under medical supervision, with dosage tailored to the individual’s clinical condition. Common adverse effects may include dizziness, headache, breast tenderness, and mild gastrointestinal disturbances. Contraindications include known hypersensitivity to progesterone or any component of the formulation, unexplained vaginal bleeding, active thromboembolic disorders, and certain hormone-dependent malignancies. Caution is advised in patients with hepatic impairment or a history of cardiovascular disease. Gestate SR 300 Tablet should be stored in a cool, dry place, protected from light and moisture. Proper adherence to prescribed dosing regimens is critical to achieving optimal therapeutic outcomes.