Genericart Glimepiride+Metformin+Pioglitazone 2mg/500mg/15mg Tablet SR
Genericart Glimepiride+Metformin+Pioglitazone 2mg/500mg/15mg Tablet SR
Glimepiride (2mg) + Metformin (500mg) + Pioglitazone (15mg)
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About This Medicine
Product description & overview
Genericart Glimepiride+Metformin+Pioglitazone 2mg/500mg/15mg Tablet SR is a combination oral antidiabetic medication indicated for the management of type 2 diabetes mellitus, particularly in patients inadequately controlled on monotherapy or dual therapy. This formulation contains Glimepiride, a sulfonylurea that stimulates pancreatic beta-cell insulin secretion; Metformin, a biguanide that decreases hepatic glucose production and improves peripheral insulin sensitivity; and Pioglitazone, a thiazolidinedione that enhances insulin sensitivity in adipose tissue, muscle, and the liver. The sustained-release (SR) formulation allows for a gradual release of the active ingredients, promoting better glycemic control and improved patient compliance through reduced dosing frequency. This combination targets multiple pathophysiological defects of type 2 diabetes, thereby optimizing blood glucose regulation. It is essential to monitor blood glucose levels regularly and adjust the dosage based on therapeutic response and tolerability. Caution is advised in patients with renal or hepatic impairment, heart failure, or a history of lactic acidosis. Common adverse effects may include gastrointestinal disturbances, hypoglycemia, weight gain, and edema. This medication should be used as part of a comprehensive diabetes management plan including diet, exercise, and regular monitoring under medical supervision.
Active composition
Metformin 500 mg
+2 more active ingredients
About Metformin
Metformin is an oral antihyperglycemic agent used to manage type 2 diabetes mellitus. It works by decreasing glucose production in the liver and improving insulin sensitivity. Metformin is effective in controlling blood sugar levels and preventing diabetes-related complications. In summary, Metformin is vital for managing type 2 diabetes.
How It Works
Metformin reduces hepatic glucose production and enhances peripheral insulin sensitivity, lowering blood glucose levels.
All Active Ingredients
Glimepiride
Glimepiride stimulates insulin secretion from pancreatic beta cells and enhances insulin sensitivity in peripheral tissues, facilitating glucose uptake and lowering blood sugar levels.
Pioglitazone
Pioglitazone activates peroxisome proliferator-activated receptor gamma (PPAR-γ), enhancing insulin sensitivity and glucose metabolism.
Dosage & How to Use
Dosage information not available. Please consult your doctor or pharmacist.
Safety Advice
Important precautions
Side Effect Occurrence
Based on clinical trials and patient reports.
Overall Tolerance
Most patients tolerate well
Common Side Effects
Safety Advice
Alcohol
It is unsafe to consume alcohol with Genericart Glimepiride+Metformin+Pioglitazone 2mg/500mg/15mg Tablet SR.
High Risk
Pregnancy
Genericart Glimepiride+Metformin+Pioglitazone 2mg/500mg/15mg Tablet SR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
Driving
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
Exercise Caution
Liver
Genericart Glimepiride+Metformin+Pioglitazone 2mg/500mg/15mg Tablet SR should be used with caution in patients with liver disease. Dose adjustment of Genericart Glimepiride+Metformin+Pioglitazone 2mg/500mg/15mg Tablet SR may be needed. Please consult your doctor. Use of Genericart Glimepiride+Metformin+Pioglitazone 2mg/500mg/15mg Tablet SR is not recommended in patients with severe liver disease.
Regular Checkup
Breastfeeding
Genericart Glimepiride+Metformin+Pioglitazone 2mg/500mg/15mg Tablet SR is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Consult Doctor
Kidney
Genericart Glimepiride+Metformin+Pioglitazone 2mg/500mg/15mg Tablet SR should be used with caution in patients with kidney disease. Dose adjustment of Genericart Glimepiride+Metformin+Pioglitazone 2mg/500mg/15mg Tablet SR may be needed. Please consult your doctor. Use of Genericart Glimepiride+Metformin+Pioglitazone 2mg/500mg/15mg Tablet SR is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.
Regular Checkup
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