Gemcox Tablet contains Etoricoxib 90 mg, a selective cyclooxygenase-2 (COX-2) inhibitor used primarily for the management of pain and inflammation associated with osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and acute gouty arthritis. Etoricoxib exerts its therapeutic effects by selectively inhibiting the COX-2 enzyme, thereby reducing the synthesis of prostaglandins responsible for inflammation, pain, and fever, while sparing COX-1, which helps maintain gastrointestinal mucosal integrity. This selective action results in effective analgesia and anti-inflammatory benefits with a potentially lower risk of gastrointestinal adverse effects compared to non-selective nonsteroidal anti-inflammatory drugs (NSAIDs). Gemcox is indicated for patients requiring long-term management of chronic inflammatory conditions or short-term relief of acute musculoskeletal pain. It should be used with caution in patients with cardiovascular risk factors, renal impairment, or a history of gastrointestinal ulcers. Common side effects may include headache, dizziness, hypertension, and gastrointestinal discomfort. Gemcox Tablet should be administered as prescribed by a healthcare professional, with dosage adjustments based on clinical response and tolerability. Regular monitoring of blood pressure, renal function, and liver enzymes is recommended during prolonged therapy to ensure safety and efficacy.