Gastractiv 10mg Tablet contains Domperidone, a dopamine D2 receptor antagonist used primarily as an antiemetic and prokinetic agent. It is indicated for the relief of nausea and vomiting associated with various conditions such as gastroesophageal reflux disease (GERD), delayed gastric emptying, and functional dyspepsia. Domperidone works by enhancing gastrointestinal motility and accelerating gastric emptying without affecting gastric acid secretion. Additionally, it increases the tone of the lower esophageal sphincter, thereby reducing reflux symptoms. Gastractiv is typically administered orally at a dose of 10mg, with the frequency determined by the severity of symptoms and clinical judgment. It is generally well-tolerated, though potential side effects include dry mouth, abdominal cramps, and, rarely, extrapyramidal symptoms or cardiac arrhythmias, particularly in patients with predisposing factors or when used at higher doses. Caution is advised in patients with underlying cardiac conditions, liver impairment, or those taking medications that prolong the QT interval. Gastractiv should be used under medical supervision, and patients should report any adverse effects promptly. It is contraindicated in individuals with known hypersensitivity to domperidone or prolactin-releasing pituitary tumors. Regular monitoring may be necessary during prolonged therapy.