Fenolip 145 Tablet contains Fenofibrate 145mg, a lipid-modifying agent primarily used to manage hyperlipidemia and hypertriglyceridemia. Fenofibrate works by activating peroxisome proliferator-activated receptor alpha (PPARα), which increases the oxidation of fatty acids and reduces the production of triglycerides and very low-density lipoprotein (VLDL) cholesterol. This action helps lower elevated levels of triglycerides and low-density lipoprotein (LDL) cholesterol while increasing high-density lipoprotein (HDL) cholesterol, thereby improving the overall lipid profile. Fenolip 145 is prescribed to patients with primary hypercholesterolemia, mixed dyslipidemia, or severe hypertriglyceridemia to reduce the risk of pancreatitis and cardiovascular disease. It is typically used alongside diet, exercise, and lifestyle modifications for optimal lipid control. The tablet is usually taken once daily with food to enhance absorption and minimize gastrointestinal discomfort. Common side effects may include gastrointestinal symptoms, headache, and muscle pain, while serious adverse effects are rare but can include liver enzyme abnormalities and rhabdomyolysis. Regular monitoring of liver function tests and lipid levels is recommended during therapy. Fenolip 145 should be used cautiously in patients with renal impairment and is contraindicated in those with severe liver disease or gallbladder disorders.