Esam 5 Tablet contains S-Amlodipine 5 mg, a calcium channel blocker primarily indicated for the management of hypertension and angina pectoris. S-Amlodipine, the pharmacologically active enantiomer of amlodipine, exerts its therapeutic effect by inhibiting the influx of calcium ions through L-type calcium channels in vascular smooth muscle and cardiac muscle, leading to vasodilation and decreased peripheral vascular resistance. This results in lowered blood pressure and improved myocardial oxygen delivery, thereby reducing the frequency and severity of anginal attacks. Esam 5 is typically prescribed for patients requiring effective blood pressure control to reduce the risk of cardiovascular events such as stroke and myocardial infarction. It is also beneficial in managing chronic stable angina and vasospastic angina. The tablet is administered orally, usually once daily, with or without food. Common side effects may include peripheral edema, headache, dizziness, and flushing, which are generally mild and transient. Caution is advised in patients with severe hepatic impairment or heart failure. Regular monitoring of blood pressure and clinical response is recommended to optimize dosage. Esam 5 Tablet should be used under medical supervision to ensure safety and efficacy in the treatment of cardiovascular conditions.